The software makes the very high poly things you wish to do easier, yes, but in no way does it take out the originality or creativity. Sure, it lets you control a ridiculous amount of polys without much lagging at all, and add small details with ease, but it doesn't fix any topology, instead it ends up a messy mesh. Remember you still control the program, it's almost like virtual sculpting.
You cannot use Zbrush models for things like animations because the topology is awful. On the other hand, you can use the high poly model to create a displacement map that you would then use on a model with good topology, but the model with good topology could not be created in Zbrush.
So yes, it makes some things easier, though to be good you still have to have the basic 3d skills. Still, in my opinion making the tool easier to create the art frees you up a bit in the creativity department. The creative and artistic control is still all in your hands!